You need to disinfect your lenses every time you remove them. If you have daily-wear soft contacts, you will clean and disinfect them every night. If you have extended-wear soft contacts, you will clean and disinfect them every time you take them out (usually once a week). Many eye care professionals recommend removing any type of contact lenses before sleeping, regardless of the type of lens. Ask your eye doctor what he or she recommends. There are several ways to disinfect soft contact lenses. If your doctor recommends the one-step peroxide method, follow the basic procedure of cleaning, rinsing, disinfecting with the hydrogen peroxide solution, and rinsing again.